Hunger Hormones: Role of Ghrelin and Leptin in Weight Loss
Ghrelin is the hunger hormone that rises before meals and signals the brain that it's time to eat, while leptin is the satiety hormone that increases after eating and signals that enough food has been consumed. During weight loss, ghrelin levels rise and leptin decreases, causing increased hunger and reduced satiety. This is one of the main reasons dieting is difficult and why there's a tendency to regain weight. Sleep, protein intake, stress management, and slow weight loss can help balance these hormones.
What is ghrelin and how does it work?
What is leptin and why is it important for weight loss?
How does sleep affect hunger hormones?
What can I eat for better hormonal balance?
Calorie deficit alone raises ghrelin levels and decreases leptin, regardless of how full you feel. Your body senses energy deficit at a biological level and switches to survival mode, triggering increased hunger. This explains why dieting gets harder weeks later, even if you're eating the same calories as at the beginning. Your body fundamentally doesn't distinguish between intentional weight loss and starvation, responding defensively to both. Slower weight loss, refeed days, and adequate protein and fiber intake can reduce this effect, but you can't completely turn off the biological instinct.
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